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Objective@#To investigate the influence of inflammatory factors on semen parameters in the seminal plasma of obese men.@*METHODS@#Based on the body mass index (BMI), 171 males were divided into a normal group (BMI 0.05).@*CONCLUSIONS@#The levels of TNF-α and IL-6 are increased and that of VEGF decreased in the seminal plasma of obese males, which may affect the semen quality.
Subject(s)
Humans , Male , Body Mass Index , Enzyme-Linked Immunosorbent Assay , Interleukin-6 , Obesity , Overweight , Semen , Chemistry , Semen Analysis , Methods , Sperm Count , Sperm Motility , Spermatozoa , Tumor Necrosis Factor-alpha , Vascular Endothelial Growth Factor AABSTRACT
Objective To evaluate of velocity vector imaging technology in methadone maintenance treatment patients. Methods From June to December in 2011,78 cases of heroin addicts were selected as observation group,and 78 healthy persons who received physical examination at the same period were selected as the control group.Velocity vector imaging technology was measured for both groups.Results All of early diastolic peak velocity and early diastolic max strain rate of the basement,left ventricular interval before,left ventricular apex,left ventricular wall between basement,in the left ventricular wall,the left ventricular segmental wall apex in observation group were significantly lower than that in the control group (P <0.05).Conclusion The velocity vector imaging technology could be applied to evaluate left ventricular function among methadone maintenance treatment patients.
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<p><b>OBJECTIVE</b>To observe the clinical effect of Sizi Zhongwang Capsule (SZC) combined with Western medicine (WM) in treating male sterility.</p><p><b>METHODS</b>Two hundred and sixty-one male patients with sterility were assigned to 3 groups, 64 in the WM group were treated with conventional Western medical therapy alone, 87 in the SZC group were treated with SZC alone, and 110 in the combined group were treated with SZC combined Western medical therapy. The treatment lasted for 90 days in total. Changes of semen related parameters before and after treatment were observed, and the conditions of pregnancy in patients' spouse were followed-up.</p><p><b>RESULTS</b>The difference in semen related parameters before and after treatment showed insignificant in the WM group (P > 0.05), but it did show statistical significance in the SZC group and the combined group (P < 0.05, P < 0.01). Moreover, the best effect was shown in the combined group, showing significant difference to the other two groups (P < 0.01, P < 0.05). The pregnancy rate of patients' spouse in the combined treated group was higher than that in the other two groups (P < 0.01, P < 0.05).</p><p><b>CONCLUSION</b>SZC combined with Western medical therapy could effectively improve the quality of semen in males with infertility and enhance the pregnancy rate in their spouse.</p>
Subject(s)
Female , Humans , Male , Pregnancy , Combined Modality Therapy , Drugs, Chinese Herbal , Therapeutic Uses , Infertility, Male , Drug Therapy , Pregnancy Rate , Semen AnalysisABSTRACT
<p><b>OBJECTIVE</b>To study the clinical application and effects of Yuziwan in the treatment of male sterility patient with abnormal protamine.</p><p><b>METHODS</b>The changes of protamine, semen and sex hormones of 30 male sterility patients treated by Yuziwan were observed before and after the treatment.</p><p><b>RESULTS</b>After a 3-month course of treatment, 9 cases were cured, 15 obviously improved and 6 failed to respond. The ratio of histone to protamine was decreased from (1.34 +/- 0.52) before the treatment to (0.72 +/- 0.32) after it, with significant difference (P < 0.01), the semen quality obviously improved (P < 0.05), and the LH and T levels markedly raised (P < 0.01). Yuziwan evidently improved the abnormal protamine, sperm quality and endocrine function of the sterility patients.</p><p><b>CONCLUSION</b>Yuziwan has good curative effect on male sterility.</p>
Subject(s)
Adult , Humans , Male , Drugs, Chinese Herbal , Therapeutic Uses , Histones , Metabolism , Infertility, Male , Drug Therapy , Metabolism , Phytotherapy , Protamines , MetabolismABSTRACT
0.05), and revealed highly significant difference compared with those of water samples collected from families of GI group with 1_year residential history (P